Rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae by use of the new chromogenic βLacta test

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Abstract

The chromogenic βLacta test developed for the rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae revealed good performance with extended-spectrum β-lactamase (ESBL) producers (97.5% true-positive results). However, false-negative results occurred with chromosomal AmpC hyperproducers and plasmid AmpC producers, whereas uninterpretable results were mostly due to VIM-1 carbapenemase producers and possibly low levels of expressed ESBLs. © 2014, American Society for Microbiology. All Rights Reserved.

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Morosini, M. I., García-Castillo, M., Tato, M., Gijón, D., Valverde, A., Ruiz-Garbajosa, P., & Cantón, R. (2014). Rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae by use of the new chromogenic βLacta test. Journal of Clinical Microbiology, 52(5), 1741–1744. https://doi.org/10.1128/JCM.03614-13

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