Therapeutic options and management approach on thalassemia an overview

Abstract

People with thalassemia, the body produces an aberrant form of hemoglobin, a hereditary blood condition that runs in families. Anemia is caused by this disorder, which causes a significant number of red blood cells to be destroyed. Iron overload, cardiac arrhythmia, hepatitis, osteoporosis, and endocrine disorders are the primary problems that thalassemia patients confront; however, anemia can also present with conventional symptoms. Treatment options for thalassemia patients are based on how serious their condition is. The standard form of treatment for thalassemia is blood transfusion. The names of thalassemia syndromes are based on the defective hemoglobin produced or the globin chain that is impacted. Thus, Mutations in the β-globin gene result in β-thalassemia, while mutations in the α-globin gene cause α-thalassemia. This review covers the various forms of thalassemia, as well as its diagnosis, prevalence, complications, and management.