Association of health literacy with medication knowledge, adherence, and adverse drug events among elderly veterans

Abstract

Health literacy is an important priority in health care delivery, but its effect on clinical outcomes remains incompletely elucidated. This observational cohort study examined the association of health literacy with medication knowledge, adherence, and adverse drug events among cognitively intact veterans older than 65 years old who were taking 5 or more medications and who were enrolled in a Veterans Administration primary care clinic. Health literacy was determined by the Rapid Estimate of Adult Literacy in Medicine. Medication knowledge and adherence were assessed by clinical pharmacist interview and refill data. Adverse drug events were determined by interview and chart review at 3 and 12 months. The 310 subjects had a mean age of 74 years, 99% were White, and 97% were male. Percentage of medications known was 29% for the low health literacy group versus 49% (marginal) and 56% (adequate), p