Bone imaging

Abstract

The search for elements which were metabolically similar to calcium in their uptake in the bone hydroxyapatite crystal has been abandoned in favor of a more empirical approach which exploits the nearly ideal physical and chemical properties of (99m)Technetium. This radionuclide forms complexes with multiple compounds. It is labeled to phosphorus containing molecules to form a bone seeking radiopharmaceutical which may give superior images of bony anatomy.