Hematological changes in patients with COVID-19 (Review)

Abstract

In December 2019, an emergence of pneumonia was detected in patients infected with a novel coronavirus (CoV) in Wuhan (Hubei, China). The International Committee on Taxonomy of Viruses named the virus severe acute respiratory syndrome-C oV-2 and the disease CoV disease-19 (CO VID- 19). Patients with CO VID- 19 present with symptoms associated with respiratory system dysfunction and hematological changes, including lymphopenia, thrombocytopenia and coagulation disorders. However, to the best of our knowledge, the pathogenesis of CO VID- 19 remains unclear. Therefore, understanding the mechanisms underlying the hematological changes that manifest during CO VID- 19 may aid in the development of treatments and may improve patient prognosis.