Active LDL trafficking drives atherosclerosis

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Abstract

The scavenger receptor class B member 1 (SRB1) in endothelial cells mediates active transcellular transport of circulating LDL into the artery wall and thereby drives the accumulation of LDL in macrophages, which become foam cells and promote the development of atherosclerosis

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APA

Fernández-Ruiz, I. (2019, July 1). Active LDL trafficking drives atherosclerosis. Nature Reviews Cardiology. Nature Publishing Group. https://doi.org/10.1038/s41569-019-0210-5

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