Using the Electronic Health Record to Facilitate Drug Allergy Delabeling

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Abstract

Purpose of Review: There is a growing number of allergy delabeling programs across diverse clinical specialties and care settings. The electronic health record (EHR) can be leveraged to facilitate allergy delabeling. The purpose of this review is to describe EHR tools that have been used in allergy delabeling programs. We also provide recommendations for organizations considering EHR-based allergy delabeling workflows that incorporate clinical informatics best practices. Recent Findings: Recent literature describes several EHR tools used in delabeling. These tools can be organized around the steps of the allergy delabeling workflow: 1. Identify eligible patients, 2. Risk stratify, 3. Evaluation and testing, 4. Documentation of outcome, 5. Delabeling, and 6. Allergy label reconciliation. Summary: Standardized EHR tools across the allergy delabeling workflow can lead to successful delabeling and support of diverse stakeholders. Partnering with EHR vendors presents an opportunity to make these tools readily available and improve allergy documentation.

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Molloy, M. J., Yan, A. P., Wilson, A. E., Beus, J., & Hess, L. M. (2025, December 1). Using the Electronic Health Record to Facilitate Drug Allergy Delabeling. Current Allergy and Asthma Reports. Springer. https://doi.org/10.1007/s11882-025-01229-2

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