Synthesis of Cored Dendrimers with Internal Cross-Links

Abstract

Hydrolytic removal of the core unit and cross-linking of their wedges enables dendrimers to be "cored" (see schematic representation). By internalizing the alkenes, the ring-closing metathesis reaction will "stitch" the dendritic wedges to gather intramolecularly, even at dendrimer concentrations of 10-3M. In contrast peripheral alkenes react intermolecularly at this concentration.