Array CGH in Fetal Medicine Diagnosis

Abstract

About 2% to 5% of live births have at least one identifiable congenital anomaly at birth (Kalter and Warkany, 1983), ranging from mild to severe abnormalities that compromise the survival. Congenital malformations have been showing increasing importance as a cause of suffering and harm to health of the population, accounting for a large percentage of perinatal morbidity and mortality (De Galan-Roosen et al., 1998, Rosano et al., 2000, Cornel, 2000).