TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

M. Luana Poeta; Judith Manola; Meredith A. Goldwasser; Arlene Forastiere; Nicole Benoit; Joseph A. Califano; John A. Ridge; Jarrard Goodwin; Daniel Kenady; John Saunders; William Westra; David Sidransky; Wayne M. Koch

Journal ArticleOPEN ACCESS

TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

Poeta M
Manola J
Goldwasser M
et al.

New England Journal of Medicine (2007) 357(25) 2552-2561

DOI: 10.1056/nejmoa073770

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427Readers

Abstract

The abrogation of function of the tumor-suppressor protein p53 as a result of mutation of its gene, TP53, is one of the most common genetic alterations in cancer cells. We evaluated TP53 mutations and survival in patients with squamous-cell carcinoma of the head and neck.

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APA

Poeta, M. L., Manola, J., Goldwasser, M. A., Forastiere, A., Benoit, N., Califano, J. A., … Koch, W. M. (2007). TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck. New England Journal of Medicine, 357(25), 2552–2561. https://doi.org/10.1056/nejmoa073770

TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

Abstract

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