Risk factors for gallstone disease in Shanghai: An observational study

Abstract

The purpose of this study was to evaluate related risk factors for gallstone disease in Shanghai.We analyzed successive physical examinations of 2288 adults who were recruited at the Jinshan Branch of the Sixth People's Hospital of Shanghai and Jinshan Hospital Affiliated to Fudan University Hospital from July 2010 to December 2012. The odds ratios (ORs) with 95% confidence intervals (CIs) were used to measure the influence factors on the risks of gallstone development.The incidence of gallstone disease was 4.11% (94/2,288). Older age (OR: 1.02; 95% CI: 1.00-1.03; P=.039), higher body weight (OR: 1.02; 95% CI: 1.00-1.04; P=.021), alanine transaminase activity (ALT) (OR: 1.02; 95% CI: 1.01-1.03; P=.001), total standard bicarbonate (SB) (OR: 1.04; 95% CI: 1.02-1.06; P