Electrochemical Bioencapsulation of Nanomaterials into Collagen for Biomedical Applications

Abstract

Here we reported a novel electrochemical encapsulation method to encapsulate various nanomaterials and bimolecules into collagen. The electrochemical encapsulation process involves assembling of collagen along with Nano/bio materi-als using an isoelectric focusing mechanism. We have showed that a wide range of Nanomaterials such as carbon nano-tubes, polymeric nanoparticles, magnetic calcium phosphate nanoparticles and biomolecules can be encapsulated into collagen. These novel collagen-based composite materials possess improved electric, mechanical, antimicrobial, mag-netic, bioactive properties. Thus, this novel electrochemical encapsulation process offers a means to fabricate novel bio-materials for various biomedical applications such as tendon/ligament, nerve, skin tissue engineering, tendon/liga-ment to bone grafts, and sutures, etc.