Bacillomycin f, a new antibiotic of iturin group: Isolation and characterization

Abstract

Bacillomycin F, a new family of iturin group antibiotics, was isolated from Bacillus subtilis. It shows a potent antifungal activity and a narrow spectrum against bacteria. Acid hydrolysis gave a peptide moiety which contains 7 mole of amino acids: D-Asp2, l-g1u1, L-Thr1, L-Pro1, D-Tyr1 and a lipid moiety which is a mixture of two main long chain β-amino acids: 3-amino-14-methylpentadecanoic acid (58%) and 3-amino-14-methylhexadecanoic acid (23%). © 1982, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.