Effects of dentifrices on artificial caries like lesions: An in vitro pH cycling study

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Abstract

Aim: To evaluate remineralising effects of three dentifrices, Vicco® by Vicco Labs, India, Perioe Cavity Care® by LG Care, Korea and Colgate Total® by Colgate-Palmolive, Thailand on artificial caries like lesions. Design: In vitro single-section and pH cycling model. Methods: Extracted third molars were painted with nail varnish, leaving 1mm wide windows before placing demineralising solution for 96h to produce artificial carious lesions 150-200μm deep. Teeth were then cut longitudinally into 100-150μm thick sections and randomly assigned to three groups. Polarised light microscopy and microradiography were used to evaluate lesion depth, before and after the 10 day pH cycle. Sections in Group A were treated with Vicco® by Vicco Labs, India (-ve control), Group B were treated with Perioe Cavity Care® by LG Care, Korea and Group C were treated with Colgate Total® by Colgate-Palmolive, Thailand. Results: Mean lesion depths in Groups B and C reduced by 7% and 12% respectively, whereas lesion depth increased by 13% in Group A. Comparisons made among groups using ANOVA and Student-Newman-Keuls tests showed that three groups were significantly different from each other (p<0.05). Conclusions: Perioe Cavity Care® and Colgate Total® remineralised initial carious lesions. However, the remineralising potential of Colgate Total® was higher than that of Perioe Cavity Care®. © 2007 FDI/World Dental Press.

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Rana, R., Itthagarun, A., & King, N. M. (2007). Effects of dentifrices on artificial caries like lesions: An in vitro pH cycling study. International Dental Journal, 57(4), 243–248. https://doi.org/10.1111/j.1875-595X.2007.tb00127.x

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