Impact of Parasitic Infections on Host Metabolism: An Overview

Abstract

The eukaryotic unicellular or multicellular hetero-specific organisms (Parasites) those are physiologically or metabolically dependent on the host for nutrition and shelter can cause diverse impact in the host patho-physiology by manipulating their immune system. The impact of parasitic infections on host metabolism can have far-reaching consequences depending on the type of parasite, the location of the infection and the duration of the infection which may include growth stunting, cognitive impairment and increased susceptibility to other diseases. Understanding these metabolic effects is crucial for developing effective strategies to prevent and treat parasitic infections, as well as mitigating their long-term consequences on host health and development. The parasites have deleterious morbid effect on the body of the host that leads to the secondary metabolic disorders like diabetes, hypertension and cardiovascular disorders. Beside these, parasites aids in the alteration of the cellular regulation of the affected host and microbiota of the gut cells. In this review the positive and negative feedback of the parasites on the host with exemplary illustrations has been discussed.