Estudos químicos e biológicos de microgramma vacciniifolia (langsd. & fisch.) copel (polypodiaceae)

Abstract

Chemical studies with aerial parts of Microgramma vacciniifolia (Langsd. & Fisch.) Copel, afforded ß-sitosterol, hopan-22-ol, 6-metoxiapinenin-7-0-ß-D-allopyranosiae and a mixture containing ethyl esters of carboxilic acias. The structures of the coumpounnds were eluciadated by spectroscopy and GC-MS analysis. The total phenolics contents of the cruáe extract and fractions were determined by Folin-Ciocalteau method. The antioxidant activity was evaluated using the 2,2-áiphenyl-l- picrylhyadrazyl (DPPH). The AcOEt fraction showeá better activity in DPPH assay (9.9 ± 0.03 μg/mL), and presented also higher contents of the total phenolic (93.60 ± 1.11 μg/mg). Antimicrobial and allelopathic effects of the crude etanolic extract and fractions also were evaluatead. In addition, the combination of biological activities was discussed.