Cytotoxic T lymphocytes: Sniping cancer stem cells

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Abstract

Cancer stem cells (CSCs)/cancer-initiating cells (CICs) are characterized as a small population of cancer cells that have high tumor-initiating ability. CSCs/CICs are resistant to several cancer therapies, and eradication of CSCs/CICs is essential to cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be a promising answer. © 2012 Landes Bioscience.

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Hirohashi, Y., Torigoe, T., Inoda, S., Morita, R., Kochin, V., & Sato, N. (2012). Cytotoxic T lymphocytes: Sniping cancer stem cells. OncoImmunology. https://doi.org/10.4161/onci.1.1.18075

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