A means of estimating the molecular masses of proteins

Abstract

The publication of two articles by Pat Andrews on the estimation of protein molecular masses by gel filtration sparked a frenzy of interest and activity in the 1960s, an era marked by a pronounced shift in emphasis of biochemical research towards an understanding of biology at the molecular level. Unlike many research fashions, this one has flourished for the best part of 50 years and shows no sign of abating. In that period the first of those articles has attracted almost 5000 citations, and the second is approaching the 4000 mark: numbers which place both papers in the top-ten most cited Biochemical Journal articles. Their consideration as BJ Classics is thus well merited.