Langerhans cell (eosinophilic) granulomatosis

Abstract

Eosinophilic granuloma (Langerhans cell granulomatosis) is the only basically nondermatological disorder consistently associated with the Langerhans cell. Its clinical manifestations are protean. There is much circumstantial evidence to suggest that this disease is fundamentally immunologic. This is consistent with current concepts about the Langerhans cell.