Ring-opening of non-activated aziridines with [11C]CO2via novel ionic liquids

Abstract

Novel ionic liquids based on DBU and DBN halide salts were developed as a catalytic system for ring-opening of non-activated aziridines with [11C]CO2. The ability of ionic liquids to activate aziridines represents a simple methodology for the synthesis of 11C-carbamates and can be extended for CO2-fixation in organic and radiochemistry.