Background: Randomized trials have been underpowered to determine an effect of intravascular ultrasound (IVUS) guidance on hard outcomes for drug-eluting stent (DES) implantation. Methods and Results: Randomized trials that compared IVUS guidance vs. angiographic guidance for DES implantation were included; 10 trials with 5,060 patients. IVUS guidance was associated with a lower incidence of cardiovascular death (odds ratio [OR] 0.44, 95% CI 0.26–0.75), and myocardial infarction (OR 0.55, 95% CI 0.32–0.94). Conclusions: IVUS-guidance is associated with a lower incidence of cardiovascular death and myocardial infarction in the era of DES. These findings should encourage operators to use IVUS more often.
CITATION STYLE
Elgendy, I. Y., Mahmoud, A. N., Elgendy, A. Y., & Mintz, G. S. (2019). Intravascular ultrasound-guidance is associated with lower cardiovascular mortality and myocardial infarction for drug-eluting stent implantation ― Insights from an updated meta-analysis of randomized trials. Circulation Journal, 83(6), 1410–1413. https://doi.org/10.1253/circj.CJ-19-0209
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