Abstract
Dendritic cell (DC)-based vaccines designed to target cancer stem cells (CSC) can induce significant antitumor responses via conferring host anti-CSC immunity. Our recent studies have demonstrated that CSC-DC vaccine could inhibit metastasis of primary tumors and induce humoral immune responses against cancer stem cells. This approach highlights the promise of cancer stem cell vaccine in cancer immunotherapy.
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Zhou, L., Lu, L., Wicha, M. S., Chang, A. E., Xia, J. chuan, Ren, X., & Li, Q. (2015). Promise of cancer stem cell vaccine. Human Vaccines and Immunotherapeutics, 11(12), 2796–2799. https://doi.org/10.1080/21645515.2015.1083661
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