A case report on a successful resection after FOLFIRI plus cetuximab therapy for unresectable colorectal cancer with multiple liver metastases

Abstract

The patient was a 66-year-old woman with a history of right breast cancer 20 years prior. Her chief complaint was hemato-chezia, and she was diagnosed as having rectal cancer. She underwent laparoscopic high anterior resection. We made a diagnosis of moderately differentiated adenocarcinoma, type 2, 25×20mm, pMP, pNO, Stage I, KRAS being wild-type. Multiple liver metastases were detected 6 months after the surgery. Tumor contacted with grison. The tumor was not completely resected as evidenced by the small liver remnant volume. Conversion therapy was administered, and the patient received 6 courses of FOLFIRI plus cetuximab therapy. Alopecia and grade 1 eruption were observed as adverse effects of the chemotherapy. The tumor size was reduced, and we resected the tumor by performing right lobectomy and partial hepatecto-my. At 1 year 3 months after surgery, no recurrence was observed.