Theranostic Imaging of Yttrium-90

Abstract

This paper overviews Yttrium-90 ( 90 Y) as a theranostic and nuclear medicine imaging of 90 Y radioactivity with bremsstrahlung imaging and positron emission tomography. In addition, detection and optical imaging of 90 Y radioactivity using Cerenkov luminescence will also be reviewed. Methods and approaches for qualitative and quantitative 90 Y imaging will be briefly discussed. Although challenges remain for 90 Y imaging, continued clinical demand for predictive imaging response assessment and target/nontarget dosimetry will drive research and technical innovation to provide greater clinical utility of 90 Y as a theranostic agent.