Gout - Risks, comorbidities and associations

Abstract

Being the most common inflammatory arthritis, gout is highly associated to several comorbidities that have important consequences on patient’s prognosis and are related to a frequent premature mortality. The study aimed to analyse the type and frequency of gouty arthritis related comorbidities, by testing for correlations between plasma level of uric acid and a series of clinical features and laboratory markers associated with inflammatory status, metabolic abdormalities and systemic complications. After analysing the results, we noticed the presence of comorbidities in signficant percentages, directly correlated to serum uric acid levels. Our observations underline the necesity of a complex evaluation, in order to reveal even subclinical associated pathologies and prevent possible events, with an input on patients’ prognosis.