Ocular dimensions in the heredity of angle-closure glaucoma

Abstract

A study of certain ocular dimensions in index patients with angle-closure glaucoma and in their first-degree relatives (siblings and offspring) is described. The value obtained for each dimension in each index patient or relative was compared with the value obtained for a normal subject of closely matched age, sex, and refractive error. Four dimensions were found to differ significantly from the normal in the index patients, siblings, and offspring; these were, anterior chamber depth, lens thickness, corneal diameter, and corneal height. The possible means of genetic transmission for these dimensions is considered and related to the suggested modes of inheritance for angleclosure glaucoma.