Role of breast cancer inhibitors on diabetes mellitus- an in silico approach

Abstract

Background: Breast cancer and diabetes mellitus type-2 are two of the major diseases, which cause death to the women worldwide. Around 16% of the breast cancer patients also suffer from diabetes mellitus. It has been noted that the risk of occurrence of the breast cancer is more in patients suffering from diabetes mellitus.Methods: Owing to this, the present article deals with an objective of using the breast cancer inhibitors for the diabetes drug target- 1ADS. Ten breast cancer inhibitors were drawn using Marvin Sketch. The docking was performed using Molegro software (Molegro Virtual Docker, MVD).Results: The docking wizard generated 50 poses with the highest Mol Dock score -131.649.Conclusion: This investigation successfully evaluated the effect of breast cancer inhibitors on diabetes mellitus, providing a new dimension in endocrine research.