Fac- Re(CO)3Cl complexes of [2-(4-R-1 H -1,2,3-Triazol-1-yl) methyl]pyridine inverse "click" ligands: A systematic synthetic, spectroscopic, and computational study

Abstract

A series of electronically tuned fac-Re(CO)3Cl inverse pyridyl-1,2,3-triazole complexes have been synthesized in good to excellent yields (72-95%) by refluxing methanol solutions of [Re(CO)5Cl] and the substituted [2-(4-R-1H-1,2,3-triazol-1-yl)methyl]pyridine ligands (py(CH2)tri-R). The resulting rhenium(I) complexes were characterized by elemental analysis, HR-ESI-MS and IR and 1H and 13C NMR spectroscopy. Additionally, the molecular structures of three of the complexes were confirmed using X-ray crystallography. The electronic properties of this series of fac-[(py(CH2)tri-R)Re(CO)3Cl] complexes were examined using UV-vis, Raman, and emission spectroscopy and cyclic voltammetry techniques. The complexes exhibit intense absorptions in the UV region, which were modeled using time-dependent density functional theory (TD-DFT). The calculations suggest that the lower energy part of the absorption band is MLCT in nature and additional higher energy π-π* transitions are present. The electronic spectra are nearly identical for all except where R = 4-nitrophenyl, suggesting that the 1,2,3-triazolyl unit acts as an electronic insulator. The TD-DFT calculations suggest that the lowest energy MLCT transition is polarized to the pyridine moiety for all complexes except the nitro-substituted one. With R = 4-nitrophenyl the MLCT is directed to an acceptor MO polarized to the triazole-R moiety. This finding is supported by resonance Raman studies that show enhancement of modes associated with the triazole-R group. The complexes are weakly emissive at room temperature with quantum yields <10-3 and correspondingly short excited-state lifetimes (τ < 20 ns). The electrochemistry of the complexes is defined by quasi-reversible Re oxidation and irreversible triazole-based ligand reduction processes. The nitro-substituted complexes show additional nitrobenzene-type reduction features. Consistent with the spectroscopic data, the positions of the oxidation and reduction processes are essentially unaffected by the electronic nature of the 2-(4-R-1H-1,2,3-triazol-1-yl)pyridine substituent. © 2013 American Chemical Society.