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Inhibitors that activate

  • Cichowski K
  • Jänne P
Nature (2010) 464(7287) 358-359
DOI: 10.1038/464358a
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Abstract

Inhibitors of RAF enzymes can suppress or activate the same signalling pathway. The details of how this happens provide a cautionary note for those targeting the pathway for anticancer drug discovery

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Cichowski, K., & Jänne, P. A. (2010). Inhibitors that activate. Nature, 464(7287), 358–359. https://doi.org/10.1038/464358a

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