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Gene Disruption and Biochemical Characterization of Verruculogen Synthase of Aspergillus fumigatus

ChemBioChem (2011) 12(5) 711-714
DOI: 10.1002/cbic.201000562
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Abstract

Three in one: Verruculogen synthase FtmF is a key enzyme to diversify the fumitremorgin biosynthetic pathway in Aspergillus fumigatus: FtmF catalyzes not only endoperoxide bond formation of verruculogen but also the deprenylation and oxidation of fumitremorgin B to yield 12α,13α-dihydroxyfumitremorgin C and 13-oxoverruculogen, respectively. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Kato, N., Suzuki, H., Takagi, H., Uramoto, M., Takahashi, S., & Osada, H. (2011). Gene Disruption and Biochemical Characterization of Verruculogen Synthase of Aspergillus fumigatus. ChemBioChem, 12(5), 711–714. https://doi.org/10.1002/cbic.201000562

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