Genetic studies on ribose 5 phosphate isomerase mutants of Escherichia coli K 12

Abstract

A gene for the constitutive ribosephosphate isomerase (rpiA) is highly cotransducible with serA at 56.2 min on the genetic linkage map of E. coli K 12. Suppression of ribosephosphate isomerase A negative mutants can occur by a regular gene mutation permitting constitutive synthesis of the normally inducible ribosephosphate isomerase B.