La Carrera de Odontología en el Contexto Actual de la Educación Superior Chilena

Abstract

Studied the hypothesis that the remaining serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) of 33 selectively-bred alcohol-preferring (P) rats have faster firing frequencies and/or increased burst activity relative to 14 alcohol-nonpreferring (NP) rats, and 32 Wistar rats. There were no significant differences among the 3 groups of rats in any of the parameters measured. Spontaneous activity was recorded from single-spiking and bursting 5-HT neurons in the DRN of unanesthetized paralyzed, alcohol-naive P, NP, and Wistar rats. Firing frequencies, the percentage of action potentials in bursts, and the percentages of bursting neurons were evaluated. The results indicate that the sample of 5-HT neurons recorded in the DRN of P rats had not compensated for a reduced number by altering neuronal activity, the proportion of action potentials in bursts, or the number of bursting neurons. ((c) 1999 APA/PsycINFO, all rights reserved)