Splenectomy in a patient with treatment-resistant visceral leishmaniasis: a case report

  • Dutra R
  • Dutra L
  • Reis M
  • et al.
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Abstract

Visceral leishmaniasis (VL), also known as Kala-azar, is a systemic infection caused by a protozoan (Leishmania) and, in its classic form, is a serious illness associated with malnutrition, anemia, hepatosplenomegaly, infectious processes and coagulopathies. The effect of splenectomy in patients with visceral leishmaniasis is not well defined; however, it is known that the spleen is the largest reservoir of infected cells belonging to the reticulo endothelial system. Therefore, the surgical procedure is an option for the debulking of parasites, providing a cure for refractory VL and minimizing the complications of hypersplenism.A leishmaniose visceral (LV) ou calazar é uma infecção sistêmica causada por um protozoário (Leishmania) e na sua forma clássica é uma doença grave. Cursa com desnutrição, anemia, hepatoesplenomegalia, processos infecciosos e coagulopatias. O papel da esplenectomia em pacientes com leishmaniose visceral não é bem definido; entretanto, sabe-se que o baço é o maior reservatório de células parasitadas do sistema reticulo endotelial e o procedimento cirúrgico é, dessa forma, uma opção para debulking de parasitas, propiciando a cura da LV refratária e minimizando as complicações do hiperesplenismo.

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APA

Dutra, R. A., Dutra, L. F., Reis, M. de O., & Lambert, R. C. (2012). Splenectomy in a patient with treatment-resistant visceral leishmaniasis: a case report. Revista Da Sociedade Brasileira de Medicina Tropical, 45(1), 130–131. https://doi.org/10.1590/s0037-86822012000100027

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