Evaluation of prognostic/diagnostic value of hematological markers in the detection of inflammation in coronavirus disease: A review study

Abstract

The Coronavirus infectious disease 2019 (COVID-19) has recently emerged as a pandemic and has endangered the lives of thousands of people worldwide. No specific treatment has been identified so far. However, the identification of diagnostic and prognostic factors in patients can be valuable for the application of preventive strategies. Increased platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), prothrombin time (PT), and D-dimer indices have been found in patients with increased inflammation and thrombosis and can lead to heart disease. Also, an increase in these indices is accompanied by worsening of the disease and impairment of the respiratory tract, which necessitates ventilation for the patients eventually. The evaluation of NLR, PLR, and coagulation parameters can be useful for identifying high-risk individuals who need to be intubated. Patient survival will improve by the timely identification and the use of appropriate treatment strategies.