Abstract
Background: Rdh54 is a motor protein that is able to dissociate Rad51 recombinase from chromatin. Results: The Rad51-binding domain of Rdh54 resides within its N terminus and is required for Rad51 removal from DNA. Conclusion: Rdh54-Rad51 interaction is important for Rad51 dissociation from chromatin but not for DNA repair. Significance: Rdh54 inhibits accumulation of toxic Rad51-DNA complexes. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Maria, S. R. S., Kwon, Y. H., Sung, P., & Klein, H. L. (2013). Characterization of the interaction between the saccharomyces cerevisiae Rad51 recombinase and the DNA translocase Rdh54. Journal of Biological Chemistry, 288(30), 21999–22005. https://doi.org/10.1074/jbc.M113.480475
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