IncP plasmid carrying colistin resistance gene mcr-1 in Klebsiella pneumoniae from hospital sewage

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Abstract

A Klebsiella pneumoniae strain of sequence type 313 (ST313) recovered from hospital sewage was found carrying the plasmid-borne colistin resistance gene mcr-1, which was bracketed by two copies of the insertion sequence ISApl1 on a 57-kb self-transmissible IncP-type plasmid of a new IncP-1 clade. The carriage of mcr-1 on a self-transmissible broad-host-range plasmid highlights that mcr-1 has the potential to spread beyond the Enterobacteriaceae family.

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APA

Zhao, F., Feng, Y., Lü, X., McNally, A., & Zong, Z. (2017). IncP plasmid carrying colistin resistance gene mcr-1 in Klebsiella pneumoniae from hospital sewage. Antimicrobial Agents and Chemotherapy, 61(2). https://doi.org/10.1128/AAC.02229-16

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