Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions

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Abstract

An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.

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Barosi, A., Dunkel, P., Guénin, E., Lalatonne, Y., Zeitoun, P., Fitton, I., … Dalko, P. I. (2020). Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions. RSC Advances, 10(6), 3366–3370. https://doi.org/10.1039/c9ra09828c

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