Oxidative Rearrangement Reactions Mediated by Hypervalent-Iodine Reagents

Abstract

During the past 40 years, hypervalent-iodine chemistry has developed rapidly and extensive attention has been received from many organic researchers. For their advantages of low toxicity, easy preparation and environmental benignity, hypervalent iodine reagents have been widely applied in various types of organic transformation including oxidative coupling, functionalization, and rearrangement reactions. Among them, there exist a series of oxidative rearrangement reactions, which can be classified into many types including C to X migration (X＝C, N or O), X to C migration (X＝N, O, S, Si or I), I to X migration (X＝O or N) and sigmatropic rearrangement. This review comprehensively summarizes the oxidative rearrangement reactions enabled by hypervalent iodine reagents, providing convenience for organic readers to learn the progress of this research field.