The effects of scopolamine hydrobromide on passive avoidance learning in rats

Abstract

In a passive-avoidance test, rats received scopolamine either before or after the shock administration. They were tested twice afterwards—on the same day and again 48 h later. On the second test, the animals were first tested in a normal state and again after administration of scopolamine or saline. Scopolamine had no effect on passive-avoidance behavior when tested on the first test on the day of shock, but it did impair performance on the second test day, 48 h later. Ss receiving scopolamine on this second test day which had also received the drug before were not impaired in the passive avoidance test. © 1969, Psychonomic Journals, Inc.. All rights reserved.