Nanosizing Approaches: Current Trends in the Solubility Enhancement of Poorly Water-soluble Drugs

0Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.

Abstract

Nanosuspension formulation and production techniques are currently undergoing remarkable growth in pharmaceutical industries to address poor aqueous solubility and low bioavailability of active pharmaceutical ingredients. It has some distinct character and benefits over other methodologies used to enhance aqueous solubility. The controlled process including formulation and processing variables provide the requisite shape and size of the drug particles in the form of nanosuspension. Generally, drug particles in the form of nanosuspension can be obtained in the size range of 200 to 1000 nm by manipulating various parameters. The pharmacokinetic parameters of the drugs can also be altered by changing the size of drug particles by developing them in the form of nanosuspension. The current review aims to address the physico-chemical characteristics of nanosuspensions, including various formulation considerations. This review also includes potential applications and recent advancements in the field of nanosizing technology.

References Powered by Scopus

Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future

1332Citations
N/AReaders
Get full text

Nanosizing: A formulation approach for poorly-water-soluble compounds

1203Citations
N/AReaders
Get full text

Nanocrystal technology, drug delivery and clinical applications

944Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Shilpi, S., Gurnany, E., Bhatt, S., Gupta, P. K., Sethiya, N. K., Jain, V., & Jain, R. (2023, July 1). Nanosizing Approaches: Current Trends in the Solubility Enhancement of Poorly Water-soluble Drugs. Indian Journal of Pharmaceutical Education and Research. Association of Pharmaceutical Teachers of India. https://doi.org/10.5530/ijper.57.3.77

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 2

67%

Lecturer / Post doc 1

33%

Readers' Discipline

Tooltip

Pharmacology, Toxicology and Pharmaceut... 2

50%

Environmental Science 1

25%

Biochemistry, Genetics and Molecular Bi... 1

25%

Article Metrics

Tooltip
Mentions
News Mentions: 1

Save time finding and organizing research with Mendeley

Sign up for free