Isolation of Flavonoid Compound and Antioxidant Activity of Salix tetrasperma Roxb. Leaves

Abstract

Salix Tetrasperma Roxb. is a plant that found in Indonesia were used as traditional medicine such as diabetes and wound healing. In this study, a flavonoid compd. of the Et acetate ext. of Salix tetrasperma Roxb. leaves was isolated by chromatog. technique and the antioxidant activity was detd. by DPPH assay. The isolation led to obtain 5,7-dihydroxy-3'-methoxyflavone based on NMR spectra. The Et acetate ext. exhibited the highest antioxidant activity with the IC50 is 65.89 μg/mL. This study shows that the Salix tetrasperma Roxb. has good potential as source of antioxidant agent. [on SciFinder(R)]