Antibacterial effect of metronidazole vs chlorhexidine solutions in treatment of root canals of primary anterior teeth

Abstract

The aim of this study was to evaluate and compare the antibacterial effect of 0.5% metronidazole, 2% chlorhexidine, and normal saline irrigant solutions against Enterococcus faecalis bacteria in the treatment of root canals of primary anterior teeth. Materials and methods: This study was carried out on sixty nonvital primary anterior teeth of Egyptian children diagnosed with ECC. These teeth were classified equally into three groups according to irrigation materials. A fresh sample was collected from each root canal after access opening before and 3 days after irrigation with the help of a paper point. The number of organisms (E. faecalis) before and after irrigation was compared for each group. Results: The bacterial count of E. faecalis was decreased in all groups however, these differences were statistically insignificant where (p <0.05). Conclusion: Both 0.5% metronidazole and 2.0% chlorhexidine appeared to be superior against E. faecalis bacteria as endodontic irrigants in pulpectomy anterior primary teeth with higher antibacterial efficacy compared to saline. Clinical significance: The success of endodontic treatment depends on the removal of microbes, from the root canals and avoidance of reinfection thus; this study provides an insight on the effects of different irrigant solutions to further help dental practitioners in the endodontic management of primary dentition.