Cholesterol efflux drives stem cell expansion in hypercholesterolaemia

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Abstract

AIBP-mediated cholesterol efflux promotes the specification of haematopoietic stem and progenitor cells (HSPCs) in embryogenesis and induces adult HSPC expansion in hypercholesterolaemic conditions, mediated by SREBP2-regulated activation of Notch signalling.

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APA

Fernández-Ruiz, I. (2019, June 1). Cholesterol efflux drives stem cell expansion in hypercholesterolaemia. Nature Reviews Cardiology. Nature Publishing Group. https://doi.org/10.1038/s41569-019-0187-0

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