Effect of the Immunomodulator (AM3®) on Biochemical Muscular Damage Markers in Basketball Players.

Abstract

The aim of this work was to explore the effects of AM3 (inmunoferón®) on markers of muscle damage in professional basketball players. Twelve professional basketball players from Tau Cerámica Vitoria Sport Team (First Spanish Professional Basketball League) participated in the study. Muscle damage and haematological related biochemical parameters and handgrip strength were performed before beginning the intervention (April), after 6 weeks of AM3 treatment (May) and after 6 weeks post-treatment (July; coinciding with Euroleague Play off Final). During all study (April-July), significant increases were observed in creatinine (1.25±0.02 vs. 1.30±0.03 mg⋅dL-1; p=0.012) and leucocyte counts (5.2±0.2 vs. 6.1±0.3 x109⋅L-1; P=0.02). However, no changes in the behaviour of the others biochemical indicators of muscular damage (CK, MB, AST, ALT, LDH), stress (cortisol) and haematological parameters (haemoglobin, haematocrit, RBC, neutrophils and lymphocytes) were presented. Regarding the handgrip strength, we detected significant higher levels in May and July with respect the April (P=0.009). The study concludes that the use of AM3 maintains or not increases the serum levels of DOMS biochemical markers, especially in players with high physical demands, and can be considered in the recovery period. ABSTRACT FROM AUTHOR