The Effect of Ginger and Thyme on Some Biochemical Parameters in Diabetic Rats

Abstract

Diabetes mellitus (DM) is one of the chronic metabolic diseases. The present study was carried out to investigate the effect of ginger and thyme on some biochemical parameters in diabetic rats. Fifty-six male albino rats were divided into eight groups; 7 rats each. Negative control, positive control and other six groups were fed standard diet with 0.5%, 1% and 5% ginger and 2%, 5% and 10% thyme respectively for six weeks. Plasma samples were separated for different biochemical analysis. Livers were kept in 10% formalin for histological study. Hemoglobin was increased in 5% ginger and 10% thyme while total protein was increased only in 5% ginger compared with diabetic group. Rats fed 5% ginger and 10% thyme showed decrease in glucose level, total cholesterol, triglycerides, LDL-C, VLDL-C, uric acid, creatinin and urea nitrogen and increase in HDL-C compared with diabetic control. Liver functions were improved in diabetic groups when they fed (5%) ginger and (10%) thyme. It could be seen that there was statistically more significant improvement in (5%) ginger than (10%) thyme in glucose and HDL-C