FORMULATION AND IN VITRO EVALUATION OF POLY-HERBAL ANTI-AGEING FACE CREAM OF CORIANDRUM SATIVUM AND ROSE HIP OIL

Abstract

Objective: The purpose of this study was to develop anti-ageing poly-herbal face cream by mixing the ethanol extract of C. sativum and rose hip oil in order to produce multipurpose effects on the skin such as fairness, softening and antiseptic effects.Methods: Ageing of the skin is the result of continuous "wear and tear" processes. Chronological skin aging is a universal and inevitable process, while in contrast, photoaging results from the UV rays of sunlight, and the damage becomes apparent in sun-exposed skin. Cream is defined as semisolid emulsions which may be oil-in-water (o/w) or water-in-oil (w/o) type and these semisolid emulsions are meant for external applications. In this study creams (o/w type) were formulated based on the anti-oxidant potential of herbal extracts and its evaluation. Coriandrum sativum plant extracted by using soxhlet method with water as solvent. The creams were formulated with coriander oil, rose hip oil with different concentrations namely F1 to F6.Results: The creams were to be stable during stability studies accordingly ICH guideline for 2 mo. Coriandrum sativum extract showed significant anti-oxidant activity with an IC50 value is 34.25 μg/ml, while for ascorbic acid the IC50 value was 46.68μg/ml.Conclusion: It can be concluded that herbal creams without side effects having antioxidant property can be used as provision of a barrier to protect the skin and avoid aging of the skin.