2-[(1R*,4R*)-1,4-Dihydroxycyclohexyl]acetic acid

Abstract

The title compound, C8H14O4, is an isolation product of the aerial parts of Senecio desfontanei. The acetic acid group is oriented at a dihedral angle of 48.03 (9)° with respect to the basal plane of the cyclohexane-1,4-diol chair. An intramolecular O - H⋯O hydrogen bond generates an S(6) ring with an envelope conformation. In the crystal, molecules are linked by O - H⋯O hydrogen bonds, resulting in R 33(20) ring motifs and C(2) O - H⋯O - H⋯O - H⋯ chains. Overall, a three-dimensional polymeric network arises. A C - H⋯O contact is also present.