Abstract
Objective: To investigate the flow-resistance of a new generation of Heat Moisture Exchanging Filters (HME filters) during 24 h of clinical use. Design: Before-after trial. Setting: A general Intensive Care Unit of a university hospital. Patients: A consecutive series of 96 patients undergoing mechanical ventilation for respiratory insufficiency of various etiology and severity. Methods: The characteristics of the secretions collected by tracheal suctioning and the pressure/flow relationship of the HMEs before and after 24h of clinical use were analyzed. Results: The resistance of the HMEs when dry was 2hPa/l·s, and its increased to a maximum of 1 hPa/l·s in 83% of the patients after 24 hours; in four patients with particularly heavy secretions HME resistance was 4-5hPa/l·s. There were no significant modifications of the secretions within the investigation period, excluding, in particular, an increase in density with consequent tracheal tube obstruction. Conclusion: The gas conditioning efficiency and design performance of the tested HMEs did not create a significant obstacle to airflow medium term mechanical ventilation; however, these devices should be cautiously used in patients with heavy bronchial secretions. © 1993 Springer-Verlag.
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Chiaranda, M., Verona, L., Pinamonti, O., Dominioni, L., Minoja, G., & Conti, G. (1993). Use of heat and moisture exchanging (HME) filters in mechanically ventilated ICU patients: Influence on airway flow-resistance. Intensive Care Medicine, 19(8), 462–466. https://doi.org/10.1007/BF01711088
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