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Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer

Nature Communications (2024) 15(1)
DOI: 10.1038/s41467-024-46531-1
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Abstract

Hyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, is common in human cancer. In this perspective, the authors review the role of the Hippo pathway in distinct tumor cell populations, discuss the impact of inhibiting Hippo output on tumor growth, and examine current developments in YAP/TAZ inhibitors.

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APA

Baroja, I., Kyriakidis, N. C., Halder, G., & Moya, I. M. (2024). Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46531-1

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