Sustained Breast Development and Breast Anthropometric Changes in 3 Years of Gender-Affirming Hormone Treatment

Abstract

Context: Breast development is important for most trans women. An important limitation of current breast development measurement methods is that these do not allow for 3D volume analyses. Objectives: To examine breast development and change in anthropometry during the first 3 years of gender-affirming hormone treatment using 3D imaging. Associations with clinical or laboratory parameters and satisfaction with the gained breast development were also studied. Design: Prospective cohort study. Setting: Specialized tertiary gender identity clinic in Amsterdam, the Netherlands. Participants: Participants were 69 adult trans women with a median age of 26 years (interquartile range, 21-38). Interventions: Gender-affirming hormone treatment. Main Outcome Measures: Volumetric and anthropometric breast development and satisfaction. Results: Breast volume increased by 72 cc (95% confidence interval [CI], 48-97) to 100 cc (standard deviation 48). This resulted in a cup-size